Effects of μ-Opioid Receptor Agonists in Assays of Acute Pain-Stimulated and Pain-Depressed Behavior in Male Rats: Role of μ-Agonist Efficacy and Noxious Stimulus Intensity

Pain is associated with stimulation of some behaviors and depression of others, and μ-opioid receptor agonists are among the most widely used analgesics. This study used parallel assays of pain-stimulated and pain-depressed behavior in male Sprague-Dawley rats to compare antinociception profiles for...

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Vydáno v:J Pharmacol Exp Ther
Hlavní autoři: Altarifi, Ahmad A., Rice, Kenner C., Negus, S. Stevens
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2015
Témata:
Behavioral Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293439/
https://ncbi.nlm.nih.gov/pubmed/25406170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.219873
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