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Abuse-related effects of mu opioid analgesics in an assay of intracranial self-stimulation in rats: modulation by chronic morphine exposure

Intracranial self-stimulation (ICSS) is an operant procedure in which responding is maintained by electrical brain stimulation. Stimulation frequency can be rapidly varied to maintain a wide range of baseline response rates, and drugs effects can be simultaneously evaluated on both low ICSS rates ma...

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Detalhes bibliográficos
Main Authors: Altarifi, Ahmad A., Rice, Kenner C., Negus, S. Stevens
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3864000/
https://ncbi.nlm.nih.gov/pubmed/23881045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e328364c0bd
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