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Determinants of Opioid Abuse Potential:Insights Using Intracranial Self-Stimulation
Intracranial self-stimulation (ICSS) is one procedure that can be used for preclinical abuse potential assessment. In ICSS procedures, subjects with microelectrodes implanted into a brain-reward region are trained to press an operant response lever for pulses of electrical brain stimulation, and dru...
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| Publicado en: | Peptides |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6342636/ https://ncbi.nlm.nih.gov/pubmed/30391425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2018.10.007 |
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