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Some determinants of morphine effects on intracranial self-stimulation in rats: dose, pretreatment time, repeated treatment and rate-dependence
Intracranial self-stimulation (ICSS) is one procedure used to evaluate abuse liability of drugs. The mu opioid receptor agonist morphine is an acknowledged drug of abuse, and the present study examined factors that may influence expression of abuse-related morphine effects on ICSS in rats. Adult mal...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3242512/ https://ncbi.nlm.nih.gov/pubmed/21921839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e32834aff54 |
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