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Differential tolerance to morphine antinociception in assays of pain-stimulated vs. pain-depressed behavior in rats

In preclinical research on pain and analgesia, noxious stimuli can stimulate expression of some behaviors (e.g. withdrawal reflexes) and depress others (e.g. feeding, locomotion, and positively reinforced operant responding). Tolerance to morphine antinociception is a robust and reliable phenomenon...

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Publicado en:Eur J Pharmacol
Main Authors: Altarifi, Ahmad A., Negus, S. Stevens
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314312/
https://ncbi.nlm.nih.gov/pubmed/25530266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2014.12.011
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