An Evolutionary Approach for Identifying Driver Mutations in Colorectal Cancer

The traditional view of cancer as a genetic disease that can successfully be treated with drugs targeting mutant onco-proteins has motivated whole-genome sequencing efforts in many human cancer types. However, only a subset of mutations found within the genomic landscape of cancer is likely to provi...

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Detaylı Bibliyografya
Yayımlandı:PLoS Comput Biol
Asıl Yazarlar: Foo, Jasmine, Liu, Lin L, Leder, Kevin, Riester, Markus, Iwasa, Yoh, Lengauer, Christoph, Michor, Franziska
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575033/
https://ncbi.nlm.nih.gov/pubmed/26379039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004350
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