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An Evolutionary Approach for Identifying Driver Mutations in Colorectal Cancer
The traditional view of cancer as a genetic disease that can successfully be treated with drugs targeting mutant onco-proteins has motivated whole-genome sequencing efforts in many human cancer types. However, only a subset of mutations found within the genomic landscape of cancer is likely to provi...
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Publicado no: | PLoS Comput Biol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4575033/ https://ncbi.nlm.nih.gov/pubmed/26379039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004350 |
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