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Intratumor Heterogeneity in Evolutionary Models of Tumor Progression
With rare exceptions, human tumors arise from single cells that have accumulated the necessary number and types of heritable alterations. Each such cell leads to dysregulated growth and eventually the formation of a tumor. Despite their monoclonal origin, at the time of diagnosis most tumors show a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3122322/ https://ncbi.nlm.nih.gov/pubmed/21406679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.125724 |
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