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Evolutionary dynamics of tumor progression with random fitness values
Most human tumors result from the accumulation of multiple genetic and epigenetic alterations in a single cell. Mutations that confer a fitness advantage to the cell are known as driver mutations and are causally related to tumorigenesis. Other mutations, however, do not change the phenotype of the...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929987/ https://ncbi.nlm.nih.gov/pubmed/20488197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tpb.2010.05.001 |
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