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Evolutionary dynamics of tumor progression with random fitness values

Most human tumors result from the accumulation of multiple genetic and epigenetic alterations in a single cell. Mutations that confer a fitness advantage to the cell are known as driver mutations and are causally related to tumorigenesis. Other mutations, however, do not change the phenotype of the...

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Bibliografski detalji
Glavni autori: Durrett, Rick, Foo, Jasmine, Leder, Kevin, Mayberry, John, Michor, Franziska
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929987/
https://ncbi.nlm.nih.gov/pubmed/20488197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tpb.2010.05.001
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