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Intratumor Heterogeneity in Evolutionary Models of Tumor Progression

With rare exceptions, human tumors arise from single cells that have accumulated the necessary number and types of heritable alterations. Each such cell leads to dysregulated growth and eventually the formation of a tumor. Despite their monoclonal origin, at the time of diagnosis most tumors show a...

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Detaylı Bibliyografya
Asıl Yazarlar: Durrett, Rick, Foo, Jasmine, Leder, Kevin, Mayberry, John, Michor, Franziska
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2011
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122322/
https://ncbi.nlm.nih.gov/pubmed/21406679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.125724
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