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An Evolutionary Approach for Identifying Driver Mutations in Colorectal Cancer
The traditional view of cancer as a genetic disease that can successfully be treated with drugs targeting mutant onco-proteins has motivated whole-genome sequencing efforts in many human cancer types. However, only a subset of mutations found within the genomic landscape of cancer is likely to provi...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | PLoS Comput Biol |
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Κύριοι συγγραφείς: | , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Public Library of Science
2015
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4575033/ https://ncbi.nlm.nih.gov/pubmed/26379039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004350 |
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