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Neutral sphingomyelinase 2 is required for cytokine-induced skeletal muscle calpain activation
Calpain contributes to infection-induced diaphragm dysfunction but the upstream mechanism(s) responsible for calpain activation are poorly understood. It is known, however, that cytokines activate neutral sphingomyelinase (nSMase) and nSMase has downstream effects with the potential to increase calp...
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| Publié dans: | Am J Physiol Lung Cell Mol Physiol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4572417/ https://ncbi.nlm.nih.gov/pubmed/26138644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00141.2015 |
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