Inhibition of neutral sphingomyelinases in skeletal muscle attenuates fatty-acid induced defects in metabolism and stress

BACKGROUND: Chronic metabolic overload leads to insulin resistance in a variety of tissues. It has been shown that exposure to saturated fatty acid palmitate can cause insulin resistance in skeletal muscle cells. Fatty acid induced synthesis of ceramide is considered to be one of the major causes fo...

Full description

Saved in:
Bibliographic Details
Main Authors: Verma, Mahesh Kumar, Yateesh, Aggunda Nagaraju, Neelima, Korrapati, Pawar, Niketa, Sandhya, Kandoor, Poornima, Jayaram, Lakshmi, Mudigere N, Yogeshwari, Sivakumaran, Pallavi, Puttrevana M, Oommen, Anup M, Somesh, Baggavalli P, Jagannath, Madanahalli R
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2014
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039661/
https://ncbi.nlm.nih.gov/pubmed/24892004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-3-255
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items