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Calcium-dependent phospholipase A(2) modulates infection-induced diaphragm dysfunction

Calpain activation contributes to the development of infection-induced diaphragm weakness, but the mechanisms by which infections activate calpain are poorly understood. We postulated that skeletal muscle calcium-dependent phospholipase A(2) (cPLA(2)) is activated by cytokines and has downstream eff...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Supinski, Gerald S., Alimov, Alexander P., Wang, Lin, Song, Xiao-Hong, Callahan, Leigh A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4896095/
https://ncbi.nlm.nih.gov/pubmed/26968769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00312.2015
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