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Muscle-specific calpastatin overexpression prevents diaphragm weakness in cecal ligation puncture-induced sepsis
Recent work indicates that infections are a major contributor to diaphragm weakness in patients who are critically ill and mechanically ventilated, and that diaphragm weakness is a risk factor for death and prolonged mechanical ventilation. Infections activate muscle calpain, but many believe this i...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4199992/ https://ncbi.nlm.nih.gov/pubmed/25170071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00975.2013 |
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