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Calpain Activation Contributes to Endotoxin-Induced Diaphragmatic Dysfunction

Calpain activation occurs in skeletal muscle in response to infection, but it is unknown if calpain inhibition improves muscle functional capacity. We hypothesized that infection induces diaphragm calpain activation, that calpain activation results in cleavage of important diaphragm cytoskeletal pro...

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Detalhes bibliográficos
Main Authors: Supinski, Gerald S., Callahan, Leigh Ann
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809221/
https://ncbi.nlm.nih.gov/pubmed/19329553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2008-0275OC
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