Overexpression of heterogeneous nuclear ribonucleoprotein F stimulates renal Ace-2 gene expression and prevents TGF-β1-induced kidney injury in a mouse model of diabetes

AIMS/HYPOTHESIS: We investigated whether heterogeneous nuclear ribonucleoprotein F (hnRNP F) stimulates renal ACE-2 expression and prevents TGF-β1 signalling, TGF-β1 inhibition of Ace-2 gene expression and induction of tubulo-fibrosis in an Akita mouse model of type 1 diabetes. METHODS: Adult male A...

Full description

Saved in:
Bibliographic Details
Published in:Diabetologia
Main Authors: Lo, Chao-Sheng, Shi, Yixuan, Chang, Shiao-Ying, Abdo, Shaaban, Chenier, Isabelle, Filep, Janos G., Ingelfinger, Julie R., Zhang, Shao-Ling, Chan, John S. D.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2015
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572079/
https://ncbi.nlm.nih.gov/pubmed/26232095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-015-3700-y
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items