Catalase Overexpression Prevents Nuclear Factor Erythroid 2–Related Factor 2 Stimulation of Renal Angiotensinogen Gene Expression, Hypertension, and Kidney Injury in Diabetic Mice

This study investigated the impact of catalase (Cat) overexpression in renal proximal tubule cells (RPTCs) on nuclear factor erythroid 2–related factor 2 (Nrf2) stimulation of angiotensinogen (Agt) gene expression and the development of hypertension and renal injury in diabetic Akita transgenic mice...

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Detalhes bibliográficos
Main Authors: Abdo, Shaaban, Shi, Yixuan, Otoukesh, Abouzar, Ghosh, Anindya, Lo, Chao-Sheng, Chenier, Isabelle, Filep, Janos G., Ingelfinger, Julie R., Zhang, Shao Ling, Chan, John S.D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2014
Assuntos:
Complications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171660/
https://ncbi.nlm.nih.gov/pubmed/24812425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1830
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