Overexpression of Angiotensinogen Increases Tubular Apoptosis in Diabetes

The intrarenal renin-angiotensin system (RAS) plays an important role in the progression of diabetic nephropathy. We have previously reported that mice overexpressing angiotensinogen in renal proximal tubular cells (RPTC) develop hypertension, albuminuria, and renal injury. Here, we investigated whe...

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Detalhes bibliográficos
Main Authors: Liu, Fang, Brezniceanu, Marie-Luise, Wei, Chih-Chang, Chénier, Isabelle, Sachetelli, Sébastien, Zhang, Shao-Ling, Filep, Janos G., Ingelfinger, Julie R., Chan, John S.D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396745/
https://ncbi.nlm.nih.gov/pubmed/18057217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007010074
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