Overexpression of Angiotensinogen Increases Tubular Apoptosis in Diabetes

The intrarenal renin-angiotensin system (RAS) plays an important role in the progression of diabetic nephropathy. We have previously reported that mice overexpressing angiotensinogen in renal proximal tubular cells (RPTC) develop hypertension, albuminuria, and renal injury. Here, we investigated whe...

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Main Authors: Liu, Fang, Brezniceanu, Marie-Luise, Wei, Chih-Chang, Chénier, Isabelle, Sachetelli, Sébastien, Zhang, Shao-Ling, Filep, Janos G., Ingelfinger, Julie R., Chan, John S.D.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2008
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396745/
https://ncbi.nlm.nih.gov/pubmed/18057217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007010074
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