Overexpression of Angiotensinogen Increases Tubular Apoptosis in Diabetes

The intrarenal renin-angiotensin system (RAS) plays an important role in the progression of diabetic nephropathy. We have previously reported that mice overexpressing angiotensinogen in renal proximal tubular cells (RPTC) develop hypertension, albuminuria, and renal injury. Here, we investigated whe...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Liu, Fang, Brezniceanu, Marie-Luise, Wei, Chih-Chang, Chénier, Isabelle, Sachetelli, Sébastien, Zhang, Shao-Ling, Filep, Janos G., Ingelfinger, Julie R., Chan, John S.D.
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2008
Sujets:
Basic Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396745/
https://ncbi.nlm.nih.gov/pubmed/18057217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007010074
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