Catalase Overexpression Prevents Nuclear Factor Erythroid 2–Related Factor 2 Stimulation of Renal Angiotensinogen Gene Expression, Hypertension, and Kidney Injury in Diabetic Mice

This study investigated the impact of catalase (Cat) overexpression in renal proximal tubule cells (RPTCs) on nuclear factor erythroid 2–related factor 2 (Nrf2) stimulation of angiotensinogen (Agt) gene expression and the development of hypertension and renal injury in diabetic Akita transgenic mice...

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Bibliografiska uppgifter
Huvudupphovsmän: Abdo, Shaaban, Shi, Yixuan, Otoukesh, Abouzar, Ghosh, Anindya, Lo, Chao-Sheng, Chenier, Isabelle, Filep, Janos G., Ingelfinger, Julie R., Zhang, Shao Ling, Chan, John S.D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Diabetes Association 2014
Ämnen:
Complications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4171660/
https://ncbi.nlm.nih.gov/pubmed/24812425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-1830
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