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Reactive Oxygen Species and Nuclear Factor Erythroid 2-Related Factor 2 Activation in Diabetic Nephropathy: A Hidden Target

Hyperglycemia, oxidative stress and renin-angiotensin system (RAS) dysfunction have been implicated in diabetic nephropathy (DN) progression, but the underlying molecular mechanisms are far from being fully understood. In addition to the systemic RAS, the existence of a local intrarenal RAS in renal...

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Detalhes bibliográficos
Publicado no:J Diabetes Metab
Main Authors: Abdo, Shaaban, Zhang, Shao-Ling, Chan, John S.D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4511631/
https://ncbi.nlm.nih.gov/pubmed/26213634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-6156.1000547
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