Tubular Deficiency of Heterogeneous Nuclear Ribonucleoprotein F Elevates Systolic Blood Pressure and Induces Glycosuria in Mice

We reported previously that overexpression of heterogeneous nuclear ribonucleoprotein F (Hnrnpf) in renal proximal tubular cells (RPTCs) suppresses angiotensinogen (Agt) expression, and attenuates systemic hypertension and renal injury in diabetic Hnrnpf-transgenic (Tg) mice. We thus hypothesized th...

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Published in:Sci Rep
Main Authors: Lo, Chao-Sheng, Miyata, Kana N., Zhao, Shuiling, Ghosh, Anindya, Chang, Shiao-Ying, Chenier, Isabelle, Filep, Janos G., Ingelfinger, Julie R., Zhang, Shao-Ling, Chan, John S. D.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6823451/
https://ncbi.nlm.nih.gov/pubmed/31673025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52323-1
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