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A local complement response by RPE causes early-stage macular degeneration

Inherited and age-related macular degenerations (AMDs) are important causes of vision loss. An early hallmark of these disorders is the formation of sub-retinal pigment epithelium (RPE) basal deposits. A role for the complement system in MDs was suggested by genetic association studies, but direct f...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Fernandez-Godino, Rosario, Garland, Donita L., Pierce, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572070/
https://ncbi.nlm.nih.gov/pubmed/26199322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv287
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