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A local complement response by RPE causes early-stage macular degeneration
Inherited and age-related macular degenerations (AMDs) are important causes of vision loss. An early hallmark of these disorders is the formation of sub-retinal pigment epithelium (RPE) basal deposits. A role for the complement system in MDs was suggested by genetic association studies, but direct f...
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| Veröffentlicht in: | Hum Mol Genet |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4572070/ https://ncbi.nlm.nih.gov/pubmed/26199322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv287 |
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