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Mouse genetics and proteomic analyses demonstrate a critical role for complement in a model of DHRD/ML, an inherited macular degeneration

Macular degenerations, inherited and age related, are important causes of vision loss. Human genetic studies have suggested perturbation of the complement system is important in the pathogenesis of age-related macular degeneration. The mechanisms underlying the involvement of the complement system a...

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Detalhes bibliográficos
Main Authors: Garland, Donita L., Fernandez-Godino, Rosario, Kaur, Inderjeet, Speicher, Kaye D., Harnly, James M., Lambris, John D., Speicher, David W., Pierce, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3857944/
https://ncbi.nlm.nih.gov/pubmed/23943789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt395
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