Complement proteins and complement regulatory proteins are associated with age-related macular degeneration stage and treatment response

Abstract Background Dysregulation of the complement system is involved in development of age-related macular degeneration (AMD). The complement cascade is regulated by membrane bound complement regulatory proteins (Cregs) on mononuclear leukocytes among others. This study aims to investigate systemi...

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Autori principali:	Alexander Kai Thomsen, Maria Abildgaard Steffensen, Jenni Martinez Villarruel Hinnerskov, Amalie Thomsen Nielsen, Henrik Vorum, Bent Honoré, Mogens Holst Nissen, Torben Lykke Sørensen
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-11-01
Serie:	Journal of Neuroinflammation
Soggetti:	Neovascular age-related macular degeneration Intermediate age-related macular degeneration Complement Complement regulatory proteins T cells Monocytes
Accesso online:	https://doi.org/10.1186/s12974-024-03273-7
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