C1q and the classical complement cascade in geographic atrophy secondary to age-related macular degeneration
Abstract Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a retinal neurodegenerative disorder. Human genetic data support the complement system as a key component of pathogenesis in AMD, which has been further supported by pre-clinical and recent clinical studies. Howe...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2022-11-01
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| Schriftenreihe: | International Journal of Retina and Vitreous |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1186/s40942-022-00431-y |
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