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C1q and the classical complement cascade in geographic atrophy secondary to age-related macular degeneration

Abstract Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) is a retinal neurodegenerative disorder. Human genetic data support the complement system as a key component of pathogenesis in AMD, which has been further supported by pre-clinical and recent clinical studies. Howe...

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Autores principales: Ted Yednock, Donald S. Fong, Eleonora M. Lad
Formato: Artigo
Lenguaje:Inglês
Publicado: BMC 2022-11-01
Colección:International Journal of Retina and Vitreous
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Acceso en línea:https://doi.org/10.1186/s40942-022-00431-y
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