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Mechanisms of amyloid formation revealed by solution NMR

Amyloid fibrils are proteinaceous elongated aggregates involved in more than fifty human diseases. Recent advances in electron microscopy and solid state NMR have allowed the characterization of fibril structures to different extents of refinement. However, structural details about the mechanism of...

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Detalhes bibliográficos
Publicado no:Prog Nucl Magn Reson Spectrosc
Main Authors: Karamanos, Theodoros K., Kalverda, Arnout P., Thompson, Gary S., Radford, Sheena E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568309/
https://ncbi.nlm.nih.gov/pubmed/26282197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnmrs.2015.05.002
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