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Mechanisms of amyloid formation revealed by solution NMR

Amyloid fibrils are proteinaceous elongated aggregates involved in more than fifty human diseases. Recent advances in electron microscopy and solid state NMR have allowed the characterization of fibril structures to different extents of refinement. However, structural details about the mechanism of...

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Bibliografiske detaljer
Udgivet i:Prog Nucl Magn Reson Spectrosc
Main Authors: Karamanos, Theodoros K., Kalverda, Arnout P., Thompson, Gary S., Radford, Sheena E.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568309/
https://ncbi.nlm.nih.gov/pubmed/26282197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnmrs.2015.05.002
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