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Mechanisms of amyloid formation revealed by solution NMR

Amyloid fibrils are proteinaceous elongated aggregates involved in more than fifty human diseases. Recent advances in electron microscopy and solid state NMR have allowed the characterization of fibril structures to different extents of refinement. However, structural details about the mechanism of...

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Dettagli Bibliografici
Pubblicato in:Prog Nucl Magn Reson Spectrosc
Autori principali: Karamanos, Theodoros K., Kalverda, Arnout P., Thompson, Gary S., Radford, Sheena E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568309/
https://ncbi.nlm.nih.gov/pubmed/26282197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnmrs.2015.05.002
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