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Mechanisms of amyloid formation revealed by solution NMR

Amyloid fibrils are proteinaceous elongated aggregates involved in more than fifty human diseases. Recent advances in electron microscopy and solid state NMR have allowed the characterization of fibril structures to different extents of refinement. However, structural details about the mechanism of...

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Dades bibliogràfiques
Publicat a:Prog Nucl Magn Reson Spectrosc
Autors principals: Karamanos, Theodoros K., Kalverda, Arnout P., Thompson, Gary S., Radford, Sheena E.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568309/
https://ncbi.nlm.nih.gov/pubmed/26282197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnmrs.2015.05.002
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