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Structure Based Thermostability Prediction Models for Protein Single Point Mutations with Machine Learning Tools

Thermostability issue of protein point mutations is a common occurrence in protein engineering. An application which predicts the thermostability of mutants can be helpful for guiding decision making process in protein design via mutagenesis. An in silico point mutation scanning method is frequently...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Jia, Lei, Yarlagadda, Ramya, Reed, Charles C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567301/
https://ncbi.nlm.nih.gov/pubmed/26361227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138022
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