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Structure Based Thermostability Prediction Models for Protein Single Point Mutations with Machine Learning Tools
Thermostability issue of protein point mutations is a common occurrence in protein engineering. An application which predicts the thermostability of mutants can be helpful for guiding decision making process in protein design via mutagenesis. An in silico point mutation scanning method is frequently...
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Publicat a: | PLoS One |
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Autors principals: | , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Public Library of Science
2015
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4567301/ https://ncbi.nlm.nih.gov/pubmed/26361227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138022 |
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