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Improving the Accuracy of Protein Thermostability Predictions for Single Point Mutations
Accurately predicting the protein thermostability changes upon single point mutations in silico is a challenge that has implications for understanding diseases as well as industrial applications of protein engineering. Free energy perturbation (FEP) has been applied to predict the effect of single p...
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| Publicado no: | Biophys J |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7335905/ https://ncbi.nlm.nih.gov/pubmed/32533939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.05.020 |
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