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Structure Based Thermostability Prediction Models for Protein Single Point Mutations with Machine Learning Tools

Thermostability issue of protein point mutations is a common occurrence in protein engineering. An application which predicts the thermostability of mutants can be helpful for guiding decision making process in protein design via mutagenesis. An in silico point mutation scanning method is frequently...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jia, Lei, Yarlagadda, Ramya, Reed, Charles C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567301/
https://ncbi.nlm.nih.gov/pubmed/26361227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138022
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