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Structure Based Thermostability Prediction Models for Protein Single Point Mutations with Machine Learning Tools

Thermostability issue of protein point mutations is a common occurrence in protein engineering. An application which predicts the thermostability of mutants can be helpful for guiding decision making process in protein design via mutagenesis. An in silico point mutation scanning method is frequently...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Jia, Lei, Yarlagadda, Ramya, Reed, Charles C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567301/
https://ncbi.nlm.nih.gov/pubmed/26361227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138022
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