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Protein asparagine deamidation prediction based on structures with machine learning methods

Chemical stability is a major concern in the development of protein therapeutics due to its impact on both efficacy and safety. Protein “hotspots” are amino acid residues that are subject to various chemical modifications, including deamidation, isomerization, glycosylation, oxidation etc. A more ac...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Jia, Lei, Sun, Yaxiong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5521779/
https://ncbi.nlm.nih.gov/pubmed/28732052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181347
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