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Structure Based Prediction of Asparagine Deamidation Propensity in Monoclonal Antibodies
Identification of asparagine (Asn) sites that are prone to deamidation is critical for the development of therapeutic monoclonal antibodies (mAbs). Despite a common chemical degradation pathway, the rates of Asn deamidation can vary dramatically among different sites, and prediction of the sensitive...
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| Publicado no: | MAbs |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6152450/ https://ncbi.nlm.nih.gov/pubmed/29958069 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2018.1478646 |
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