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Structure Based Thermostability Prediction Models for Protein Single Point Mutations with Machine Learning Tools

Thermostability issue of protein point mutations is a common occurrence in protein engineering. An application which predicts the thermostability of mutants can be helpful for guiding decision making process in protein design via mutagenesis. An in silico point mutation scanning method is frequently...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Jia, Lei, Yarlagadda, Ramya, Reed, Charles C.
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567301/
https://ncbi.nlm.nih.gov/pubmed/26361227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138022
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