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CScape: a tool for predicting oncogenic single-point mutations in the cancer genome
For somatic point mutations in coding and non-coding regions of the genome, we propose CScape, an integrative classifier for predicting the likelihood that mutations are cancer drivers. Tested on somatic mutations, CScape tends to outperform alternative methods, reaching 91% balanced accuracy in cod...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599557/ https://ncbi.nlm.nih.gov/pubmed/28912487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11746-4 |
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