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CScape: a tool for predicting oncogenic single-point mutations in the cancer genome

For somatic point mutations in coding and non-coding regions of the genome, we propose CScape, an integrative classifier for predicting the likelihood that mutations are cancer drivers. Tested on somatic mutations, CScape tends to outperform alternative methods, reaching 91% balanced accuracy in cod...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Rogers, Mark F., Shihab, Hashem A., Gaunt, Tom R., Campbell, Colin
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599557/
https://ncbi.nlm.nih.gov/pubmed/28912487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11746-4
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