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Impact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional Activity

The transcription factor STAT3 is constitutively active in many cancers, where it mediates important biological effects, including cell proliferation, differentiation, survival, and angiogenesis. The N-terminal domain (NTD) of STAT3 performs multiple functions, such as cooperative DNA binding, nucle...

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Podrobná bibliografie
Vydáno v:Mol Cell Biol
Hlavní autoři: Hu, Tiancen, Yeh, Jennifer E., Pinello, Luca, Jacob, Jaison, Chakravarthy, Srinivas, Yuan, Guo-Cheng, Chopra, Rajiv, Frank, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561728/
https://ncbi.nlm.nih.gov/pubmed/26169829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00060-15
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