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Impact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional Activity
The transcription factor STAT3 is constitutively active in many cancers, where it mediates important biological effects, including cell proliferation, differentiation, survival, and angiogenesis. The N-terminal domain (NTD) of STAT3 performs multiple functions, such as cooperative DNA binding, nucle...
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Publicado no: | Mol Cell Biol |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4561728/ https://ncbi.nlm.nih.gov/pubmed/26169829 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00060-15 |
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