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STAT5 Outcompetes STAT3 To Regulate the Expression of the Oncogenic Transcriptional Modulator BCL6

Inappropriate activation of the transcription factors STAT3 and STAT5 has been shown to drive cancer pathogenesis through dysregulation of genes involved in cell survival, growth, and differentiation. Although STAT3 and STAT5 are structurally related, they can have opposite effects on key genes, inc...

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Detalhes bibliográficos
Main Authors: Walker, Sarah R., Nelson, Erik A., Yeh, Jennifer E., Pinello, Luca, Yuan, Guo-Cheng, Frank, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719667/
https://ncbi.nlm.nih.gov/pubmed/23716595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01620-12
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