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An Isoform specific Myristylation Switch Targets Type II PKA Holoenzymes to Membranes
cAMP-dependent protein kinase (PKA) is regulated in part by N-terminal myristylation of its catalytic (C) subunit. Structural information about the role of myristylation in membrane targeting of PKA has been limited. In mammalian cells there are four functionally non-redundant PKA Regulatory subunit...
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| Publicado no: | Structure |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4558360/ https://ncbi.nlm.nih.gov/pubmed/26278174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.07.007 |
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