Structure and Allostery of the PKA RIIβ Tetrameric Holoenzyme

In its physiological state, cyclic adenosine monophosphate (cAMP)–dependent protein kinase (PKA) is a tetramer that contains a regulatory (R) subunit dimer and two catalytic (C) subunits. We describe here the 2.3 angstrom structure of full-length tetrameric RIIβ(2):C(2) holoenzyme. This structure sh...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Zhang, Ping, Smith-Nguyen, Eric V., Keshwani, Malik M., Deal, Michael S., Kornev, Alexandr P., Taylor, Susan S.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985767/
https://ncbi.nlm.nih.gov/pubmed/22323819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1213979
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker