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Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme
To provide tight spatiotemporal signaling control, the cyclic adenosine monophosphate (cAMP)-dependent protein kinase (PKA) holoenzyme typically nucleates a macromolecular complex or a “PKA signalosome.” Using the RIIβ holoenzyme as a prototype, we show how autophosphorylation/dephosphorylation of t...
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| Publicado no: | PLoS Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4497662/ https://ncbi.nlm.nih.gov/pubmed/26158466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002192 |
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