Synthesis, nicotinic acetylcholine receptor binding, in vitro and in vivo pharmacology properties of 3′-(substituted pyridinyl)-deschloroepibatidine analogs

Over the last several years we have synthesized and studied the in vitro and in vivo nAChR pharmacological properties of epibatidine (4) analogs. In this study we report the synthesis, nAChR in vitro and in vivo pharmacological properties of 3′-(substituted pyridinyl)-deschloroepibatidine analogs (5...

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Bibliografiset tiedot
Julkaisussa:Bioorg Med Chem
Päätekijät: Ondachi, Pauline W., Ye, Zhuo, Castro, Ana H., Luetje, Charles W., Damaj, M. Imad, Mascarella, S. Wayne, Navarro, Hernán A., Carroll, F. Ivy
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554999/
https://ncbi.nlm.nih.gov/pubmed/26233800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2015.07.021
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