Nicotinic Acetylcholine Receptor Efficacy and Pharmacological Properties of 3-(Substituted phenyl)-2β-substituted Tropanes

There is a need for different and better aids to tobacco product use cessation. Useful smoking cessation aids, bupropion (2) and varenicline (3), share some chemical features with 3-phenyltropanes (4), which have promise in cocaine dependence therapy. Here we report studies to generate and character...

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Detalhes bibliográficos
Main Authors: Carroll, F. Ivy, Blough, Bruce E., Mascarella, S. Wayne, Navarro, Hernán A., Eaton, J. Brek, Lukas, Ronald J., Damaj, M. Imad
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3130825/
https://ncbi.nlm.nih.gov/pubmed/21058665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm100994w
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