Synthesis of 2-(Substituted phenyl)-3,5,5-trimethylmorpholine Analogues and Their Effects on Monoamine Uptake, Nicotinic Acetylcholine Receptor Function, and Behavioral Effects of Nicotine

Toward development of smoking cessation aids superior to bupropion (2), we describe synthesis of 2-(substituted phenyl)-3,5,5-trimethylmorpholine analogues 5a–5h and their effects on inhibition of dopamine, norepinephrine, and serotonin uptake, nicotinic acetylcholine receptor (nAChR) function, acut...

Full description

Saved in:
Bibliographic Details
Main Authors: Carroll, F. Ivy, Muresan, Ana Z., Blough, Bruce E., Navarro, Hernán A., Mascarella, S. Wayne, Eaton, J. Brek, Huang, Xiaodong, Damaj, M. Imad, Lukas, Ronald J.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048909/
https://ncbi.nlm.nih.gov/pubmed/21319801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm1014555
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items