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Autophagy dysfunction upregulates beta-amyloid peptides via enhancing the activity of γ-secretase complex
Numerous studies have shown that autophagy failure plays a critical role in the pathogenesis of Alzheimer’s disease, including increased expression of beta-amyloid (Aβ) protein and the dysfunction of Aβ clearance. To further evaluate the role of autophagy in Alzheimer’s disease, the present study wa...
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| Pubblicato in: | Neuropsychiatr Dis Treat |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove Medical Press
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4547656/ https://ncbi.nlm.nih.gov/pubmed/26316755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/NDT.S84755 |
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